Monoalkylglycerol ether lipids promote adipogenesis |
| |
Authors: | Homan Edwin A Kim Yun-Gon Cardia James P Saghatelian Alan |
| |
Institution: | Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA. |
| |
Abstract: | The molecular mechanisms that lead to the generation of adipose tissue (adipogenesis) are of basic and biomedical interest. Cellular models of adipogenesis have proven extremely valuable in defining biomolecules-primarily genes and proteins-that regulate adipogenesis. Here, the analysis of differentiating adipocytes using an untargeted metabolomics approach led to the discovery of the monoalkylglycerol ethers as a natural class of adipocyte differentiation factors. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|