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Determination of Pidotimod in Human Plasma by RP-HPLC
Authors:LI Xiao-Qing  WEI Jun  YAN Ping  XIE Jian-Wei
Affiliation:Beijing Institute of Pharmacology & Toxicology, Academy of Military Medical Science, Beijing 100850, P. R. China
Abstract:Pidotimod, a synthetic dipeptid, has been shown to affect in a positive way some immune functions in humans. It induces an increase in the expression of interleukin-2-T-lymphocyte receptor and can play an important role as an immunostimulating agent, improving immunodefences. The speration and determination of pidotimod in plasma was achieved by using Zorbax Rx-Cl8 colunm. with a guard column.
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