Amperometric Determination of Norepinephrine Based on Dual-Film Modified Graphite Electrode |
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| Authors: | JU Huang-Xian NI Jing-An CHEN Hong-Yuan Leech Dónal |
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| Affiliation: | 1. Department of Chemistry, The State Key Laboratory of Coordination Chemistry, Nanjing Universiiy, Nanjing 210093, P. R. China;2. Department of Chemistry, National University of Ireland, Galway, Irelana |
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| Abstract: | Norepinephrine (NE) is one of the most important biochemical messengers. The oxidation of NE at various electrodes has been extensively studied. The ease of NE oxidation lead to the development of convenient and rapid procedures for measuring NE levels using various electrochemical methods. A serious problem is that ascorbic acid (AA) often co-exists with NE, resulting in interference in NE determinations. This work describes the electrocatalytical activity of[Os(bpy)2(PVP)10Cl]+/Nafion modified graphite electrode for trace NE determination. The modified electrode can eliminate the interference from AA and uric acid (UA) in NE determinations,thus could be used as an amperometric sensors for the detection of NE levels. |
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