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Synthesis of Ni(II), Pd(II) and Cu(II) metal complexes of novel highly functionalized aroylaminocarbo-N-thioyl pyrrolidines and their activity against fungi and yeast |
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| Authors: | Yahya Nural Rafet Kilincarslan H Ali Dondas Bekir Cetinkaya Mehmet Sami Serin Ronald Grigg Tuncay Ince Colin Kilner |
| Institution: | aDepartment of Chemistry, Faculty of Pharmacy, Mersin University, Yenisehir, 33342 Mersin, Turkey;bDepartment of Chemistry, Faculty of Science, Ege University, Bornova İzmir, Turkey;cDepartment of Microbiology, Faculty of Pharmacy, Mersin University, Yenisehir, 33342 Mersin, Turkey;dSchool of Chemistry, MIDAS Centre, Leeds University, Leeds LS2 9JT, UK |
| Abstract: | A series of Ni(II), Pd(II) and Cu(II) metal complexes of highly functionalized aroylaminocarbo-N-thioyl pyrrolidines were prepared and characterized by microanalysis, spectroscopic methods, magnetic susceptibility measurements and single crystal X-ray diffraction studies. The antifungal activity of the metal complexes against the yeast Saccharomyces cerevisae and against the fungus Penicillium digitatum was studied. |
| Keywords: | Aminocarbo-N-thioyl Pyrrolidines Acylthioureas Crystal structures Bioactivity Metal complexes |
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