| 三组分一锅法合成3-(2-喹啉基)薁甲酸甲酯衍生物 |
| |
| 引用本文： | 孙曙光,谷峥,王道林,韩珊,黄孝东.三组分一锅法合成3-(2-喹啉基)薁甲酸甲酯衍生物[J].有机化学,2009,29(6):979-984. |
| |
| 作者姓名： | 孙曙光 谷峥 王道林 韩珊 黄孝东 |
| |
| 作者单位： | 渤海大学化学化工学院,辽宁省应用化学重点实验室,锦州,121003 |
| |
| 摘 要： | 在质子酸作用下, 以1-甲酰基薁-3-甲酸甲酯、芳香胺和脂肪醛为原料, 三组分一锅法合成了一系列3-(2-喹啉基)薁甲酸甲酯衍生物. 该反应收率良好、操作简单、条件温和. 产物的结构通过红外光谱、核磁共振谱和元素分析证实, 同时给出了该反应可能的反应机理.
|
| 关 键 词： | 薁 1-甲酰基薁 3-(2-喹啉基)薁 合成 |
| 收稿时间： | 2008-7-14 |
| 修稿时间： | 2008-10-23 |
Three Component One-Pot Synthesis of Methyl 3-(2-Quinolyl)azulene-1-carboxylates |
| |
| Sun Shuguang,Gu Zheng,Wang Daolin,Han Shan,Huang Xiaodong.Three Component One-Pot Synthesis of Methyl 3-(2-Quinolyl)azulene-1-carboxylates[J].Chinese Journal of Organic Chemistry,2009,29(6):979-984. |
| |
| Authors: | Sun Shuguang Gu Zheng Wang Daolin Han Shan Huang Xiaodong |
| |
| Institution: | (Liaoning Key Laboratory of Applied Chemistry, College of Chemistry and Chemical Engineering,
Bohai University, Jinzhou 121003)
|
| |
| Abstract: | Methyl 3-(2-quinolyl)azulene-1-carboxylate derivatives were synthesized by three component one-pot condensation of methyl 1-formoylazulene-3-carboxylate, aromatic amines and alkylaldehydes under mild conditions. This method provides several advantages such as good yield and simple work-up procedure. All the products were fully characterized by 1H NMR, IR spectra and elemental analysis. |
| |
| Keywords: | azulene 1-formoylazulene-3-carboxylate 3-(2-quinolyl)azulene synthesi |
| 本文献已被 维普 万方数据 等数据库收录！ |
| 点击此处可从《有机化学》浏览原始摘要信息 |
| 点击此处可从《有机化学》下载免费的PDF全文 |
|
