On the chemical constituents of Dipsacus asper |
| |
Authors: | Tian Xiao-Yan Wang Ying-Hong Liu Hong-Yue Yu Shi-Shan Fang Wei-Shuo |
| |
Affiliation: | Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Ministry of Education), Peking Union Medicinal College and Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China. |
| |
Abstract: | Bioassay-guided fractionation of 95% EtOH extract from the roots of Dipsacus asper lead to the isolation of some phenolic acids (caffeic acid, 2,6-dihydroxycinnamic acid, vanillic acid, 2'-O-caffeoyl-D-glucopyranoside ester, and caffeoylquinic acid) as the major active components, and five new iridoid glucoside dimers (1-5) and one new iridoid glucoside monomer (6), other known iridoid glycosides loganin, cantleyoside, triplostoside A, lisianthioside, 6'-O-beta-D-apiofuranosyl sweroside, as well as triterpenoids oleanic acid and akebiasaponin D. The structures of new compounds 1-6 were determined as dipsanosides C (1), D (2), E (3), F (4), G (5), and 3'-O-beta-D-glucopyranosyl sweroside (6) by spectroscopic, including 1D and 2D NMR techniques, and chemical methods. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|