Electroanalytical Investigation and Simultaneous Determination of Etodolac and Thiocolchicoside at a Non-modified Glassy Carbon Electrode in Anionic Surfactant Media |
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Authors: | Ozge Selcuk Cem Erkmen Dr Burcin Bozal-Palabiyik Prof?Dr Bengi Uslu |
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Institution: | Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06560 Ankara, Turkey |
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Abstract: | In this study, a differential pulse voltammetry method was designed for the simultaneous determination of etodolac and thiocolchicoside in a tablet dosage form. This method is a sensitive, costless and reproducible one initially designed for the simultaneous determination of etodolac and thiocolchicoside using bare/unmodified glassy carbon electrode in the presence of sodium dodecyl sulfate. At optimized conditions, the method showed linear responses with etodolac and thiocolchicoside concentration in the range of 1 μM to 80 μM. The limits of detection and quantification were calculated as 0.11 μM and 0.38 μM for etodolac and 0.20 μM and 0.67 μM for thiocolchicoside, respectively. |
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Keywords: | Determination etodolac thiocolchicoside voltammetry anionic surfactant |
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