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An Efficient Simultaneous Electrochemical Detection of Nanomolar Epinephrine and Uric Acid using Low Temperature Synthesized Nano-sized Copper Telluride
Authors:Susmita Pradhan  Mahuya Bhattacharyya Banerjee  Dr Sudip Biswas  Dr Nor Aliya Hamizi  Prof Dipak K Das  Prof Radhaballabh Bhar  Prof Rajib Bandyopadhyay  Prof Panchanan Pramanik
Institution:1. Department of Instrumentation Science, Jadavpur University, Kolkata, 700032 India;2. Department of Instrumentation and Electronics Engineering, Jadavpur University,Salt Lake Campus, Sector-III, Kolkata, 700098 India;3. Department of Chemistry and Chemical Engineering, Yangzhou University, Jiangsu, 225009 China;4. Nanotechnology and Catalysis Research Centre, University Malaya, 50603 Kuala Lumpur, Malaysia;5. Department of Chemistry and Nanoscience, GLA University, Mathura, 281406 India;6. Department of Instrumentation and Electronics Engineering, Jadavpur University,Salt Lake Campus, Sector-III, Kolkata, 700098 India

Laboratory of Artificial Sensory Systems, ITMO University, Saint Petersburg, 199034 Russia

Abstract:Herein we developed a simple, cost effective, electrochemical sensor based on nanosized copper telluride (nps-CuTe) for simultaneous detection of epinephrine (EP) and uric acid (UA). Voltammetric responses suggests dramatical improvement of electrocatalytic properties of both molecules by incorporating CuTe nps into unmodified graphite paste electrode (bare GP). Differential pulse voltammetric (DPV) measurement depicts large potential separation of 128 mV between EP and UA, allows their simultaneous determination from binary mixture. Under optimized condition, CuTe modified graphite paste electrode (CuTe/GP) manifested linear relationships of EP and UA in the range of 5–60 μM and 5–120 μM with detection limit (S/N=3) of 18 nM and 32 nM respectively. Moreover, CuTe/GP showed satisfactory response towards pharmaceutical and clinical samples for determining EP and UA concentrations.
Keywords:copper telluride electrode  epinephrine and uric acid  electrochemical sensor
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