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A Facile Fabrication of Poly-ethionine Film on Glassy Carbon Electrode for Simultaneous and Sensitive Detection of Dopamine and Paracetamol |
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| Authors: | Ayyadurai Kannan Seenivasan Manojkumar Sivaprakasam Radhakrishnan |
| Institution: | 1. Postgraduate and Research Department of Chemistry, Vivekananda College, Tiruvedakam West, 625 234 Madurai, Tamil Nadu, India.;2. Postgraduate and Research Department of Chemistry, Vivekananda College, Tiruvedakam West, 625 234 Madurai, Tamil Nadu, India.
Battery Research Centre of Green Energy, Ming Chi University of Technology, 243 New Taipei city, Taiwan;3. Electrodics and Electrocatalysis Division, CSIR-Central Electrochemical Research Institute, Karaikudi, 630 003 Tamil Nadu, India. |
| Abstract: | An electrochemical sensor based on poly-ethionine (Poly-ET) film modified glassy carbon electrode was developed for sensitive and simultaneous sensing of dopamine (DA) and paracetamol (PA). The electropolymerization of ethionine monomer was carried out to modify the electrode. The modified electrode was characterized by using scanning electron microscopy, cyclic voltammetry and electrochemical impedance spectroscopy. The Poly-ET/GCE exhibited excellent electrocatalysis towards the sensing of DA and PA. Poly-ET/GCE showed a linear increase of current response with increase concentration of DA and PA ranging from 0.1 μM–60 μM and 0.1 μM–180 μM, respectively. The LODs were found to be 7 nM and 18 nM (S/N=3) for DA and PA, respectively. This electrochemical sensor was successfully utilized for the detection of DA and PA in pharmaceutical samples. |
| Keywords: | Electrochemical polymerization ethionine electrochemical sensor dopamine paracetamol |