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Synthesis of the entire carbon framework of the kedarcidin chromophore aglycon
Authors:Yoshimura Fumihiko  Lear Martin J  Ohashi Isao  Koyama Yasuhito  Hirama Masahiro
Institution:Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan.
Abstract:In advanced studies directed toward the total synthesis of the kedarcidin chromophore, we have successfully achieved the late-stage installation of the nine-membered diyne ring in the presence of the highly functionalised ansamacrocyclic bridge.
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