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Facile preparation of amine and amino acid adducts of [60]fullerene using chlorofullerene C60Cl6 as a precursor
Authors:Kornev Alexey B  Khakina Ekaterina A  Troyanov Sergey I  Kushch Alla A  Peregudov Alexander  Vasilchenko Alexey  Deryabin Dmitry G  Martynenko Vyacheslav M  Troshin Pavel A
Institution:IPCP RAS, Semenov Prospect 1, Chernogolovka 141432, Russia.
Abstract:We report a general synthetic approach to the preparation of highly functionalized amine and amino acid derivatives of 60]fullerene starting from readily available chlorofullerene C(60)Cl(6). The synthesized water-soluble amino acid derivative of C(60) demonstrated pronounced antiviral activity, while the cationic amine-based compound showed strong antibacterial action in vitro.
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