Ethanol‐promoted reductive homocoupling reactions of aryl halides catalyzed by palladium on carbon (Pd/C) |
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| Authors: | Linjun Shao Yijun Du Minfeng Zeng Xiudong Li Wenting Shen Shufeng Zuo Yueqing Lu Xian‐Man Zhang Chenze Qi |
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| Institution: | 1. Institute of Applied Chemistry, Shaoxing University, Shaoxing, Zhejiang Province 312000, People's Republic of China;2. College of Yuanpei, Shaoxing University, Shaoxing, Zhejiang Province 312000, People's Republic of China |
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| Abstract: | Homocoupling reactions of aryl bromides or iodides proceeded smoothly with palladium on carbon (Pd/C) catalyst, ethanol and base in dimethyl sulfoxide (DMSO) to afford exclusively symmetric biaryls in good to excellent yields. Ethanol was first used as a reducing agent in situ to reduce the Pd2+/C species into Pd0/C active species to complete the catalytic redox cycle. It was found that ethanol can promote the Pd/C‐catalyzed reductive homocoupling of aryl iodides and bromides efficiently in the presence of base. A reaction mechanism has been put forward and discussed. Copyright © 2010 John Wiley & Sons, Ltd. |
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| Keywords: | palladium biaryls aryl halides homocoupling ethanol |
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