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Oxidative ring-opening of isatins for the synthesis of 2-aminobenzamides and 2-aminobenzoates
Authors:Yu-Wei Wang  Lei Zheng  Feng-Cheng Jia  Yun-Feng Chen  An-Xin Wu
Institution:1. School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan 430073, China;2. Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, 430079, PR China
Abstract:An efficient and practical isatin-based oxidative domino protocol has been developed for the facile synthesis of 2-aminobenzamides and 2-aminobenzoates. The robust nature of this reaction system is reflected by accessible starting materials, room temperature and high-yield gram-scale synthesis.
Keywords:Oxidative domino protocol  2-Aminobenzamides  2-Aminobenzoates
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