Efficient synthesis of the antigenic phosphoglycans of the Leishmania parasite |
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| Authors: | Ruhela D Vishwakarma R A |
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| Institution: | Bio-organic Chemistry Lab, National Institute of Immunology, Aruna Asaf Ali Marg, JNU Complex, New Delhi 110067, India. |
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| Abstract: | Antigenic phosphoglycan repeats of the Leishmania parasite can be assembled in a flexible and efficient manner without involving any glycosidation steps, and the chain can be extended either towards the non-reducing (6'-OH) or reducing (1-OH) end suitable for synthesis of lipophosphoglycan, proteophosphoglycan and analogues. |
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