A convenient imino aldol reaction in ethyl alcohol catalyzed by a cation-exchange resin |
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| Authors: | Shimizu M Itohara S Hase E |
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| Institution: | Department of Chemistry for Materials, Mie University, Tsu, Mie 514-8507, Japan. |
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| Abstract: | Imino aldol reaction of ketene silyl acetals with imines proceeds smoothly to give beta-amino esters in good yields under the influence of a cation-exchange resin in ethanol, and the work-up of the reaction consists only of a simple filtration followed by concentration of the crude mixture and purification. |
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