Synthesis and Antifungal Bioactivity of Methyl 2-Methoxyimino-2-{2-[(substituted benzylidene)aminooxymethyl]phenyl}acetate and 2-Methoxyimino-2-{2-[(substituted benzylidene)aminooxy-methyl]phenyl}-N-methylacetamide Derivatives |
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| Authors: | LI Guohua YANG Hong |
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| Institution: | Department of Applied Chemistry,College of Science,Nanjing Agricultural University,Nanjing,Jiangsu 210095,China |
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| Abstract: | Ten methyl 2‐methoxyimino‐2‐{2‐(substituted benzylidene)aminooxymethyl]phenyl}acetate and 2‐methoxy‐ imino‐2‐{2‐(substituted benzylidene)aminooxymethyl]phenyl}‐N‐methylacetamide derivatives were synthesized. Structures of the new compounds were characterized by IR, 1H NMR and GC‐MS data. These compounds at 10 µg/mL were tested in vitro against five pathogenic fungi, namely, Sclerotonia, Botrytis cinerea Pers, Gibberella zeae, Rhizoctorua solani and Pyricularia oryzae. Compounds G5 , G6 , G7 and G8 showed potent antifungal activities against Botrytis cinerea Pers, G7 against Gibberella zeae and G7 , G8 against Rhizoctorua solani, respectively. |
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| Keywords: | methyl 2-methoxyimino-2-{2-[(substituted benzylidene)aminooxymethyl]phenyl}acetate methyl 2-methoxyimino-2-[2-[(substituted benzylidene)aminooxymethyl]phenyl}-N-methylacetamide synthesis antifungal activity |
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