7,8-Dioxochlorpromazine,synthesis and properties |
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Authors: | A. Zirnis J. K. Suzuki J. W. Daly A. A. Manian |
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Abstract: | 7,8-Dihydroxychlorpromazine and 2-chloro-7,8-dihydroxyphenothiazine were converted to the corresponding 7,8-dioxo compounds by oxidation with tetrachloro-o-quinone. Spectral properties indicate that the 7,8-dioxo compounds exist in zwitterionic forms reminiscent of aminochromes. The 7,8-dioxochlorpromazine is proposed as a possible metabolite of chlorpromazine. |
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