Recent Advances on Nanozyme-based Electrochemical Biosensors |
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| Authors: | Xiaoyu Wang Shaojun Dong Hui Wei |
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| Affiliation: | 1. Department of Biomedical Engineering, College of Engineering and Applied Sciences, Nanjing National Laboratory of Microstructures, Jiangsu Key Laboratory of Artificial Functional Materials, State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University, Nanjing, Jiangsu, 210023 China;2. State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022 China |
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| Abstract: | Nanozymes are nanomaterials with enzyme-like catalytic activities. The unique features of nanozymes (such as high stability, low cost, large surface area for bioconjugation, ease of storage, and multi-functionalities) offer unprecedented opportunities for designing electrochemical biosensors. Recent years have witnessed the rapid development of nanozyme-based electrochemical biosensors. To highlight these achievements, this review first discusses the representative nanozymes including peroxidase mimics, oxidase mimics, hydrolase mimics, and superoxide dismutase mimics used in electrochemical biosensors. Then, it summarizes the bioanalytical applications for the detection of various analytes. Finally, current challenges and future research directions are summarized. |
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| Keywords: | Nanozymes Electrochemical detection Biosensors Minireview |
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