Preparation and characterization of 3D collagen materials with magnetic properties |
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| Institution: | 1. MMRI/ CAPPA-D, Department of Chemical Engineering, McMaster University, Hamilton, Ontario L8S 4L7, Canada;2. 3M Canada Company, London, Ontario, Canada;1. College of Materials Science and Engineering, Shenzhen Key Laboratory of Polymer Science and Technology, Guangdong Research Center for Interfacial Engineering of Functional Materials, Nanshan District Key Lab for Biopolymers and Safety Evaluation, Shenzhen University, Shenzhen 518060, PR China;2. Key Laboratory of Optoelectronic Devices and System of Ministry Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, PR China;1. School of Mechanical, Aerospace and Civil Engineering, United Kingdom;2. North West Composites Centre, School of Materials, The University of Manchester, Manchester M13 9PL, United Kingdom;1. CIMJECT Laboratory, Department of Mechanical Engineering, Federal University of Santa Catarina, 88040-900 Florianópolis, SC, Brazil;2. Biomechanics Engineering Laboratory, University Hospital (HU), Federal University of Santa Catarina, 88040-900 Florianópolis, SC, Brazil;3. Dipartimento di Chimica, Materiali ed Ingegneria Chimica “G. Natta”, Politecnico di Milano, Edificio 6, Piazza L. da Vinci 32, 20133 Milano, Italy;1. The Key Laboratory of Polymer Processing Engineering, Ministry of Education, South China University of Technology, Guangzhou 510640, China;2. Research and Development Department, Zhejiang Zhongning Silicon Company Ltd, QuZhou 324000, China;3. School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China |
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| Abstract: | In this study 3D collagen materials with magnetic properties were prepared by lyophilization technique. Magnetic particles were synthesized by precipitation of iron (II) sulfate heptahydrate and iron (III) chloride hexahydrate in an aqueous solution of chitosan and then added to a collagen solution. Starch dialdehyde (DAS) was used as a cross-linking agent for the materials. The properties of the obtained materials were studied using infrared spectroscopy, scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Additionally, mechanical properties, porosity, density, swelling and moisture content were measured.It was found that 3D composites made from collagen with magnetic particles are hydrophilic with a high swelling ability. Cross-linking of such collagen materials with dialdehyde starch (DAS) alters the swelling degree, porosity and density of materials. The addition of magnetic particles to collagen materials decreases its porosity, and increases the density of the studied materials. Collagen 3D materials with magnetic particles are rigid and inflexible. Magnetic properties of the 3D collagen materials containing magnetic particles were confirmed by the interaction of this material with a magnet. |
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| Keywords: | Collagen Magnetic particles Chitosan Biomaterials Magnetic scaffold |
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