Electrochemical modification of a carbon paste electrode with poly (1,5-diaminonaphthalene) and copper-cobalt nanostructures for the determination of thioctic acid in real samples

This study used square-wave voltammetry and cyclic voltammetry to investigate the electrochemical oxidation of Thioctic Acid (TA) on a Carbon Paste Electrode (CPE) modified with copper-cobalt nanostructures and poly (1,5-Diaminonaphthalene). The voltammetric sensor was sensitive to the oxidation of TA. In addition, we optimized the effects of multiple cycles of deposition of Cu-Co nanostructures, and electro-polymerization of monomer 1,5-DAN, scan rate, and pH. The sensor showed good identification capabilities for TA. The linear responses obtained ranged from 0.6 μM to 150 μM with a detection limit of 0.48 μM for the modified CPE. The adsorption process controlled the oxidation of TA. We used the proposed sensor and method to determine TA in real samples.