Design and Synthesis of Chemiluminescent Cassettes Based on Energy Transfer |
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| Authors: | Steven Vertueux Dr. Alexandre Haefele Dr. Kathleen Solmont Dr. Philippe Durand Prof. Pierre-Yves Renard |
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| Affiliation: | 1. Normandie Univ, UNIROUEN INSA Rouen, CNRS, COBRA (UMR 6014), 1 rue Tesnière, 76821 Mont-Saint-Aignan Cedex, France;2. Université Paris-Saclay, CNRS, Institut de Chimie des Substances Naturelles, UPR 2301, 91198 Gif-sur-Yvette, France |
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| Abstract: | Chemiluminescent probes are being considered as a convenient option for optical imaging. Several strategies were reported to increase the probe chemiluminescence efficiency. In this study, a series of chemiluminescent cassettes based on adamantyl stabilized 1,2-dioxetanes (“Schaap's dioxetane”) linked to a fluorophore (BODIPY or dicyanoisophorone fluorophore) by a conjugated linker have been synthetized. Their chemiluminescent decomposition and the photoluminescence properties of their respective emissive species were investigated. |
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| Keywords: | chemiluminescent probe energy transfer. indirect chemiluminescence 1,2-dioxetane |
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