Tandem Sulfonylation/Cyclization of Vinyl Azides with Aryldiazonium Tetrafluoroborates and SO2 |
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| Authors: | Fayun Chen Li-Xia Quan Anxi Zhou Congbin Ji Yanhong Li Xianhong Zhu Liu-Liang Mao Prof Dr Jie-Ping Wan |
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| Institution: | 1. College of Chemistry and Environment Science, Shangrao Normal University, Shangrao, 334001 P.R. China) E-mail: Xianhong;2. College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, 330022 P.R. China |
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| Abstract: | An efficient and facile strategy for the synthesis of 6-(sulfonylmethyl)phenanthridines and its derivatives has been developed via tandem sulfonylation cyclization of vinyl azides under mild conditions in the absence of any catalysts and additives. The reaction simply utilizes easily accessible and cheap K2S2O5 as the sulfur dioxide source, delivering functionalized phenanthridines in moderate to excellent yields with operational simplicity and gram-scale synthesis, as well as good functional-group tolerance. |
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| Keywords: | K2S2O5 synthetic methods vinyl azides tandem cyclization three-component reaction |
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