A practical synthesis of 2,4(5)-diarylimidazoles from simple building blocks |
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Authors: | Zuliani Valentina Cocconcelli Giuseppe Fantini Marco Ghiron Chiara Rivara Mirko |
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Affiliation: | Dipartimento Farmaceutico, UniversitA degli Studi di Parma, V. le G.P. Usberti, 27/A, I-43100 Parma, Italy. |
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Abstract: | A simple and efficient approach to selectively obtain 2,4(5)-diarylimidazoles suppressing formation of 2-aroyl-4(5)-arylimidazoles is described. The yield of each of the two products strongly depends on the reaction conditions employed. This reaction provides a simple method to prepare small libraries of biologically active compounds by parallel synthesis. |
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