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Efficient and eco-friendly synthesis of dihydropyrimidinones, bis(indolyl)methanes, and N-alkyl and N-arylimides in ionic liquids
Authors:M Dabiri  P Salehi  M Baghbanzadeh  M Shakouri  S Otokesh  T Ekrami  R Doosti
Institution:1. Department of Chemistry, Faculty of Science, Shahid Beheshti University, Postal Code 1983963113, Evin, Tehran, Iran
2. Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, P.O. Box 19835-389, Evin, Tehran, Iran
Abstract:Dihydropyrimidinones, bis(indolyl)methanes, and N-alkyl and N-arylimides were synthesized efficiently under mild reaction conditions in the presence of two types of ionic liquids. In each section, effects of different ILs on the yield of reactions were investigated. The use of ionic liquids offer improvements for the synthesis of title compounds with regard to the yield of products, simplicity in operation, short reaction times and green aspects by avoiding toxic catalyst and organic solvents.
Keywords:
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