Application of N-halo reagents in organic synthesis |
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Authors: | E Kolvari A Ghorbani-Choghamarani P Salehi F Shirini M A Zolfigol |
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Institution: | 1. Faculty of Chemistry, Bu-Ali Sina University, Hamedan, 6517838683, Iran 2. Department of Chemistry, Faculty of Science, Ilam University, Ilam, Iran 3. Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Evin, Tehran, Iran 4. Department of Chemistry, Faculty of Science, Guilan University, Rasht, Iran
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Abstract: | This review article summarizes published data on the application of N-halo reagents (such as N-halo amines, N-halo amides and/or imides, N-halo sulfonamides and/or imides, and etc.) in various organic functional group transformations such as: oxidation reactions, deprotection and protection of different functional groups, halogenation of saturated and unsaturated compounds, acylation of alcohols, phenols, amines or thiols, epoxidation of alkenes, aziridination and etc. The main purpose of writing this review is encouraging of active researchers interested to this field for the synthesis of new N-halo reagents specially with different halogens and applications of these new N-halo reagents in organic reactions or finding more and more applications of existing N-halo reagents in organic synthesis. |
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