A new strategy for a DNA assay based on a target-triggered isothermal exponential degradation reaction |
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| Authors: | Zhao Jing Liu Tao Fan Qi Li Genxi |
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| Institution: | Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, PR China. |
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| Abstract: | An ultra-sensitive, fast, simple and easily operated method for sequence-specific detection of polynucleotides is proposed herein, which is based on a novel target-triggered isothermal exponential degradation reaction (TT-isoTexpDR) and the color change of probe-functionalized gold nanoparticles. |
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