| 超高效液相色谱-串联质谱法测定食品包装纸中的酚类化合物 |
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| 引用本文： | 王天娇,林勤保,宋欢,李波.超高效液相色谱-串联质谱法测定食品包装纸中的酚类化合物[J].分析测试学报,2010,29(12). |
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| 作者姓名： | 王天娇 林勤保 宋欢 李波 |
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| 作者单位： | 山西大学应用化学研究所;山西省出入境检验检疫局技术中心; |
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| 基金项目： | 国家质检总局科技计划资助项目 |
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| 摘 要： | 建立了食品包装纸中2,4,6-三氯酚、五氯酚、4-氯-3,5-二甲基-苯酚和4-叔-辛基酚的超高效液相色谱-串联质谱(UPLC-MS/MS)分析方法。样品经丙酮超声萃取,Oasis HLB固相柱净化后,用Waters AC-QUITY UPLC C18柱以乙腈和0.05%氨水为流动相进行分离,以负离子模式离子化,在多离子反应监测(MRM)模式下定量检测。在优化实验条件下,2,4,6-三氯酚的线性范围为20~1 000μg.L-1,五氯酚、4-氯-3,5-二甲基-苯酚和4-叔-辛基酚的线性范围为5~1 000μg.L-1,相关系数均大于0.997。4种酚类化合物的检出限为1~10μg.kg-1,定量下限为5~20μg.kg-1,加标回收率为75%~109%,相对标准偏差均不高于12.5%。该方法灵敏度高、操作简单,可用于食品包装纸中酚类化合物含量的快速检测。
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| 关 键 词： | 食品包装纸 烷基酚 氯酚 固相萃取 超高效液相色谱-串联质谱 |
Determination of Phenols in Food Packaging Paper by Ultra Performance Liquid Chromatography Tandem Mass Spectrometry |
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| WANG Tian-jiao,LIN Qin-bao,SONG Huan,LI Bo.Determination of Phenols in Food Packaging Paper by Ultra Performance Liquid Chromatography Tandem Mass Spectrometry[J].Journal of Instrumental Analysis,2010,29(12). |
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| Authors: | WANG Tian-jiao LIN Qin-bao SONG Huan LI Bo |
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| Institution: | WANG Tian-jiao1,LIN Qin-bao1,SONG Huan2,LI Bo1(1.Institute of Applied Chemistry,Shanxi University,Taiyuan 030006,China,2.Shanxi Border Inspection and Quarantine Bureau,Taiyuan 030024,China) |
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| Abstract: | An ultra performance liquid chromatography-tandem mass spectrometric(UPLC-MS/MS)method was developed for the detectermination of phenols,including 2,4,6-trichlorophenol(TCP),pentachlorophenol(PCP),4-chloro-3,5-dimethylphenol(SPMX)and 4-tert-octylphenol(4-tert-OP,in paper for food packaging.Ultrasonic extraction with acetone and Oasis HLB solid-phase column purification was used.The separation was carried out on an ACQUITY UPLC C18 column using a mobile phase consisting of acetonitrile and 0.05% ammonia.The ... |
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| Keywords: | food packaging paper alkylphenol chlorophenols solid-phase extraction UPLC-MS/MS |
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