|
|||||
|
|
Asymmetric synthesis of fagomine |
|
| Affiliation: | University of Toyama, Department of Chemistry, Gofuku3190, Toyama 930-8555, Japan |
| Abstract: | We report an asymmetric synthesis of the alkaloid fagomine, which is an inhibitor of mammalian α-glucosidase and β-galactosidase, by means of Sharpless asymmetric dihydroxylation and Pd(II)-catalyzed cyclization, starting from 3-(t-butoxylcarbonylamino)propanol. |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ | |