Changes of porous poly(ε-caprolactone) bone grafts resulted from e-beam sterilization process |
| |
| Institution: | 1. Department of Polymer Engineering, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem Rakpart 3, Hungary;2. Research Center for Biomechanics, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem Rakpart 3, Hungary;3. Institute of Applied Radiation Chemistry, Technical University of Lodz, 93-590 Lodz, Wroblewskiego 15, Poland;1. Hungarian Academy of Sciences, Institute of Isotopes, Budapest, Hungary;2. Hungarian Academy of Sciences, Institute of Isotopes, Budapest, Hungary;1. Institute of Nuclear Techniques, Budapest University of Technology and Economics, Műegyetem rkp. 9, H-1111 Budapest, Hungary;2. Institute of Chemistry, Faculty of Science, Eötvös Loránd University, Pázmány Péter sétány 1/A, , H-1117 Budapest, Hungary;3. Department of Nuclear Medicine, RWTH University Hospital Aachen, .Pauwelsstr. 30, D-52074 Aachen, Germany;4. Biological Nanochemistry Research Group, Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences of the Hungarian Academy of Sciences, Magyar tudósok körútja 2, , H-1117 Budapest, Hungary;5. Institute for Nuclear Research of the Hungarian Academy of Sciences, Bem tér 18/c, H-4026 Debrecen, Hungary;6. Institute of Neuroscience and Medicine, Forschungszentrum Jülich, D-52425 Jülich, Germany;1. Department of Biochemistry, Faculty of Medicine, Taif University, Al Taif, Saudi Arabia;2. Departments of Biochemistry, Faculty of Medicine, Zagazig University, Zagazig, Egypt;3. Department of Surgery, Faculty of Medicine, Taif University, Al Taif, Saudi Arabia;4. General Organization for Teaching Hospitals and Institutes, Egypt;5. Department of Anatomy and Histology, Faculty of Medicine, Taif University, Al Taif, Saudi Arabia;6. Departments of Histology, Faculty of Medicine, Zagazig University, Zagazig, Egypt;1. Magneto-plasmonic Lab, Laser and Plasma Research Institute, Shahid Beheshti University, Tehran, Iran;2. Physics Department, Shahid Beheshti University, Tehran, Iran;3. Department of Materials Engineering, Hamedan University of Technology, Hamedan, Iran |
| |
| Abstract: | The most important mechanical feature of poly(ε-caprolactone) (PCL) foams applied in bone tissue engineering as a scaffold, has been investigated as a function of irradiation dose. Radiation is proposed for the sterilization of the polymer before the implantation. Polycaprolactone scaffold foams were obtained by combination of compression molding and particulate leaching techniques. The porogen was changed in the range 74–96 w% and the irradiation dose was varied from 25 to 150 kGy. Our results show that yield strength is not a function of radiation dose, but is rather influenced by the porosity, while the critical strain is mainly dependent on the dose. All these together mean that the modulus of the elasticity of PCL foams is dependent on both the porosity and the dose. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
