Acyclic β-amino acid catalyzed asymmetric anti-selective Mannich-type reactions |
| |
| Institution: | Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE-106 91 Stockholm, Sweden |
| |
| Abstract: | The ability of a primary amine containing acyclic β3-amino acids to catalyze direct asymmetric anti-selective Mannich-type reactions is presented. The reactions are generally highly diastereo- and enantioselective to give the corresponding Mannich products with up to >19:1 dr (anti/syn) and 88–99% ee. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
