Fractals related to long DNA sequences and complete genomes |
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| Affiliation: | 1. Helomics™ Corporation, Pittsburgh, PA, United States;2. Magee-Womens Hospital of UPMC, Pittsburgh, PA, United States;3. Palo Alto Medical Foundation/Research Institute, Sutter Cancer Research Consortium, San Francisco, CA, United States;4. The Western Pennsylvania Hospital, Pittsburgh, PA, United States;5. Washington University School of Medicine, St. Louis, MO, United States;6. Yale University School of Medicine, New Haven, CT, United States;7. University of Texas MD Anderson Cancer Center, Houston, TX, United States |
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| Abstract: | In visualizing very long DNA sequences, including the complete genomes of several bacteria, yeast and segments of human genes, we encounter fractal-like patterns underlying these biological objects of prominent importance. The method used here to visualize genomes of organisms may well be used as a convenient tool to trace, e.g., evolutionary relatedness of species. We describe the method and explain the origin of the observed fractal-like patterns. |
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