A general access to 1,1-cyclopropane aminoketones and their conversion into 2-benzoyl quinolines |
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Authors: | Zhenjun Mao Haijun Qu Yanyan Zhao Xufeng Lin |
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Institution: | Department of Chemistry, Zhejiang University, Hangzhou 310027, China. lxfok@zju.edu.cn. |
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Abstract: | 1,1-Cyclopropane aminoketones were efficiently synthesized in high yields by the tandem reaction of α-amino aryl ketones with vinyl sulfonium salts using DBU as the base in CH(2)Cl(2). This methodology was utilized to synthesize 2-benzoyl quinolines. |
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