TRANSPORT STUDIES ON MACROMOLECULES USED AS DRUG CARRIERS |
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| Authors: | P V Kulkarni S B Rajur P P Antich T M Aminabhavi M I Aralaguppi |
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| Institution: | 1. Advanced Radiological Sciences Department of Radiology , The University of Texas Southwestern Medical Center at Dallas , Dallas, Texas, 75235;2. Department of Chemistry , Karnatak University , Dharwad, 580003, India;3. Lamar University , Beaumont, Texas, 77710;4. Department of Chemistry , Karnatak University , Dharwad, 580003, India |
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| Abstract: | Abstract Modecular transport of drugs through carier polymeric materds has been an active area of research. A number of soluble polymers have been used to deliver the drugs selectively to specific parts of the body. The literature in this area of research is extensive and diverse. An effort has been made to review the transport of drug molecules through physiological systems via polymeric materials. A brief introduction to the fundamentals and concepts which are frequently used in the drug-delivery area are covered in the following sections. Various aspects of the problems related to polymer-drug complexes, carrier molecules, and their degradability have been discussed. Both natural and synthetic biopolymers have been included in the discussion. Only representative references during the period 1977–1989 have been used in the discussion of results, and thus the reader is advised to look further into the original literature for greater information. |
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