Synthesen und Reaktionen von Pyridazinderivaten, 2. Mitt.: 4-Hydroxymethyl-pyridazin

While reduction of ethylpyridazine-4-carboxylate (1 b) by LiAlH₄ or NaBH₄ yields mixtures of 4-hydroxymethyl-pyridazine (1 a) and ethyl-2.5-dihydro-pyridazine-4-carboxylate (2), pyridazine-4-carbaldehyde and 4-acetyl-pyridazine quantitatively by NaBH₄ are reduced to the corresponding carbinols1 a, 1 d. 4-Chloromethyl-pyridazine easily can be prepared by reaction of1 a with SOCl₂. The structures of the new compounds are proved by¹H-NMR-, IR- and mass-spectroscopy.

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1. Mitt.:G. Heinisch, Mh. Chem.104, 953 (1973).