| Enantioselective Addition of Diethylzinc to Benzaldehyde by Catalysts of Chiral Heterocyclic Ligands |
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| 引用本文： | Yan HE, Yue Lan LI, Ye Di GUAN(Department of Chemistry,Peking University,Beijing 100871). Enantioselective Addition of Diethylzinc to Benzaldehyde by Catalysts of Chiral Heterocyclic Ligands[J]. 中国化学快报, 1999, 0(9) |
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| 作者姓名： | Yan HE Yue Lan LI Ye Di GUAN(Department of Chemistry Peking University Beijing 100871) |
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| 作者单位： | Department of Chemistry，Peking University，Beijing 100871 |
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| 摘 要： | TheenantioselectiveadditionofdiethylzincreagentstoprochiralcarbonylgrouphasbeenachievedprincipallybycatalyticalamountofchiralP-aminoalcoholswhichhaveproventobehighlyeffectivecatalysts'.Ahydroxylgrouphasbeenregardedtobenecessaryforthechiralligandtoformazincalkoxideasthecatalyticspecies'.Wewishtoreporthereinontheethylationofbenzaldehydewithdiethylzincpromotedbyseveralkindsofoxazolidineandthiazolidinederivativeswhichdonotcontainhydroxylgroup.Fourkindschiralheterocyclicligandsweusedarelistedasfoll…
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Enantioselective Addition of Diethylzinc to Benzaldehyde by Catalysts of Chiral Heterocyclic Ligands |
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| Yan HE, Yue Lan LI, Ye Di GUAN. Enantioselective Addition of Diethylzinc to Benzaldehyde by Catalysts of Chiral Heterocyclic Ligands[J]. Chinese Chemical Letters, 1999, 0(9) |
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| Authors: | Yan HE Yue Lan LI Ye Di GUAN |
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| Abstract: | Several kinds of chiral heterocyclic ligands without hydroxyl group have beensynthesized and used as catalysts for the asymmetric addition of diethylzinc to benzaldehyde.These ligands promoted the formation of (S)-1-phenylpropanols in good yields and medium togood enantioselectivities (50 ~ 86 % ee. ). |
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| Keywords: | Chiral heterocyclic ligands. hydroxyl group asymmetric catalysis. enantioselectivity. |
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