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Stereo- and regio-controlled aldol synthesis
Authors:Isao Kuwajima  Masahiro Kato  Akio Mori
Institution:Department of Chemistry, Tokyo Institute of Technology, Ookayama, Meguro-ku, Tokyo 152 Japan
Abstract:Treatment of (Z)-trimethylsilyl enol ethers with dibutylboryl trifluoromethanesulfonate followed by removal of trimethylsilyl triflate generated and addition of aldehydes affords the corresponding erythro aldols with almost complete stereo- and regio-selectivities.
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