Synthese,spektroskopische Charakterisierung und bakterizide Wirksamkeit neuer Organylbis(thiophenolato)bismut(III)-Komplexe

New Organobis(thiophenolate)bismuth(III) derivatives C₆H₅Bi(SC₆H₄Cl-p)₂ (I), Ch₃Bi(SC₆H₄NH₂-p)₂ (II) and CH₃AS(SC₆H₄NH₂-p)₂ (III) can be prepared by the reaction of phenyldibromobismuth(III), methyldibromobismuth(III) and -arsenic(III), respectively, with stoichiometric amounts of lithium-p-chlorothiophenolate (for I), and lithium-p-aminothiophenolate. II reacts with an excess of iodomethane to form the bis(mercaptoanilinium) complex CH₃Bi(SC₆H₄NH₂CH₃-p₂]²⁺ (I⁻)₂ (IV). Treating IV with adequate amounts of AgNO₃ or TINO₃ yields the analogous nitrate derivative CH₃Bi(SC₆H₄NH₂CH₃-p)₂]²⁺ (NO₃⁻)₂ (V). The new compounds were characterized by elemental analysis, ¹H NMR, IR and mass spectroscopy and some of the compounds were also characterized by vapour pressure molecular weight osmometry too.The microbiological effect of the organometallic arsenic(III)- and bismuth(III)-bis(thiolates) I-IV was studied, the bismuth compounds generally inhibited bacterial growth more than the arsenic derivative. The aminothiophenolate complexes II and IV in particular were not inferior to the well-known organothiolatomercury(II) complexes with regard to their inhibition of bacterial growth. The hydrophilic mercaptoanilinium derivative IV has potential as a novel bactericide.