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The analysis of biomedical hydroxyapatite powders and hydroxyapatite coatings on metallic medical implants by near-IR Fourier transform Raman spectroscopy
Institution:1. Department of Analytical Chemistry, University of Valencia, 50 Dr. Moliner Street, 46100 Burjassot, Valencia, Spain;2. Department of Earth Sciences, University of Pisa, Via S. Maria 53, 56126 Pisa, Italy;3. Sagunto Archaeological Museum, 23 del Castillo Street, 46500 Sagunto, Valencia, Spain;4. Applied and Laser Spectroscopy Lab., ICCOM-CNR, Via G. Moruzzi 1, 56124 Pisa, Italy;1. Instituto de Restauración del Patrimonio, Universitat Politècnica de València, Camino de Vera s/n, 46022 Valencia, Spain;2. Museo Nacional de Arqueología Subacuática, Paseo del Muelle Alfonso XII, 22. 30202 Cartagena. Murcia, Spain;3. Museu de Prehistòria de València, Corona 36, 46003, Valencia, Spain;1. Academy of Fine Arts in Prague, ALMA Laboratory, U Akademie 4, 170 22 Prague 7, Czech Republic;2. Institute of Inorganic Chemistry of the Czech Academy of Sciences, ALMA Laboratory, 250 68 Husinec-Řež, Czech Republic;3. Institute of Scientific Instruments of the Czech Academy of Sciences, Environmental Electron Microscopy Group, Královopolská 147, 612 64 Brno, Czech Republic;4. Institute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University, Grudziadzka 5, 87-100 Toruń, Poland
Abstract:In this paper we discuss the application of Fourier transform Raman (FTR) spectroscopy to the in situ analysis of the inorganic bioceramic hydroxyapatite in both powder form and as a thermally sprayed hydroxyapatite coating on metals currently employed in medical implants for orthopaedic surgery. The derivation of the FTR spectrum of hydroxyapatite is attempted by the analysis of the pure powders of its known constituents. The FTR spectra of hydroxyapatite powders sintered up to 1300°C suggest significant structural changes in the region of 1250°C. The FTR spectra of coated metal systems clearly distinguish between samples of differing crystallinity and provide some information on the effect of the coating process on the hydroxyapatite material. The preliminary examination of hydroxyapatite coated dental screws shows a change in the nature of the hydroxyapatite coating on recovery after clinical use.
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