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4-Oxobenzo[d]1,2,3-triazin-pyridinium-phenylacetamide derivatives as new anti-Alzheimer agents: design,synthesis, in vitro evaluation,molecular modeling,and molecular dynamic study |
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| Authors: | Hosseini Fahimeh Mohammadi-Khanaposhtani Maryam Azizian Homa Ramazani Ali Tehrani Maliheh Barazandeh Nadri Hamid Larijani Bagher Biglar Mahmoud Adibi Hossein Mahdavi Mohammad |
| Institution: | 1.Department of Chemistry, University of Zanjan, P.O. Box 45195-313, Zanjan, Iran ;2.Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran ;3.Department of Medicinal Chemistry, School of Pharmacy-International Campus, Iran University of Medical Sciences, Tehran, Iran ;4.Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran ;5.Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran ;6.Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran ; |
| Abstract: | Structural Chemistry - A new series of 4-oxobenzod]1,2,3-triazin-pyridinium-phenylacetamide hybrids 8a–p was designed, synthesized, and screened as the potential cholinesterase inhibitors... |
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