Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells |
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Authors: | Smith David G Law Ga-lai Murray Benjamin S Pal Robert Parker David Wong Ka-Leung |
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Affiliation: | Department of Chemistry, Durham University, South Road, Durham, UK DH1 3LE. |
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Abstract: | Image and spectral intensity from bicarbonate-selective europium(III) probes localised in the mitochondria of cells is modulated reversibly by variation of external pCO(2), and is suppressed by addition of the carbonic anhydrase inhibitor, acetazolomide. |
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