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Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells
Authors:Smith David G  Law Ga-lai  Murray Benjamin S  Pal Robert  Parker David  Wong Ka-Leung
Affiliation:Department of Chemistry, Durham University, South Road, Durham, UK DH1 3LE.
Abstract:Image and spectral intensity from bicarbonate-selective europium(III) probes localised in the mitochondria of cells is modulated reversibly by variation of external pCO(2), and is suppressed by addition of the carbonic anhydrase inhibitor, acetazolomide.
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