| An Improved Synthesis of trans-3,3b,4,9b,10,11-Hexahydro -6-methoxy-9b-methyl-7- (1-methylethyl) phenanthro {1,2-c[furan-1,5-dione]} |
| |
| 作者姓名： | Xue Qiang YIN Guang Zhong YANG Yuan Chao LI* Shanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai |
| |
| 作者单位： | Xue Qiang YIN， Guang Zhong YANG， Yuan Chao LI* Shanghai Institute of Materia Medica， Chinese Academy of Sciences，Shanghai 200031 |
| |
| 摘 要： | The diterpenoid triexpoxides lactone triptolide is a potent antileukemic, antiflammatory, immunosuppressive and antifertile principle of Tripterygium wilfordii Hook f.1,2. Many methods of synthesis of this compound have been reported in which trans-3,3b,4,9b,10, 11-hexahydro-6-methoxy-9b-methyl-7- (1-methylethyl) phenanthro {1,2-c furan-1,5- dione]} 4 was an important intermediate. In one reported synthesis, compound 4 was obtained by CrO3/AcOH oxidation of triptophenolide methyl ether 1, b…
|
| 关 键 词： | Tripterygium wilfordii， triptolide， triptophenolide methyl ether . |
An Improved Synthesis of trans-3,3b,4,9b,10,11-Hexahydro -6-methoxy-9b-methyl-7- (1-methylethyl) phenanthro {1,2-c[furan-1,5-dione]} |
| |
| Xue Qiang YIN, Guang Zhong YANG, Yuan Chao LI* Shanghai Institute of Materia Medica, Chinese Academy of Sciences,Shanghai .An Improved Synthesis of trans-3,3b,4,9b,10,11-Hexahydro -6-methoxy-9b-methyl-7- (1-methylethyl) phenanthro {1,2-c[furan-1,5-dione]}[J].Chinese Chemical Letters,2001(7). |
| |
| Authors: | Xue Qiang YIN Guang Zhong YANG Yuan Chao LI |
| |
| Institution: | Xue Qiang YIN, Guang Zhong YANG, Yuan Chao LI* Shanghai Institute of Materia Medica, Chinese Academy of Sciences,Shanghai 200031 |
| |
| Abstract: | |
| |
| Keywords: | |
| 本文献已被 CNKI 等数据库收录！ |
|
