| pH响应型碳点的荧光机制和生物医学应用 |
| |
| 引用本文： | 何松杰,张清梅,张路鹏,杜秀娟,陈峰华,李冰.pH响应型碳点的荧光机制和生物医学应用[J].发光学报,2022(1):137-151. |
| |
| 作者姓名： | 何松杰 张清梅 张路鹏 杜秀娟 陈峰华 李冰 |
| |
| 作者单位： | 太原科技大学应用科学学院;福建师范大学物理与能源学院福建省量子调控与新能源材料重点实验室;山西医科大学口腔医学院 |
| |
| 基金项目： | 国家自然科学基金(11704274);福建省量子调控与新能源材料重点实验室开放课题(QMNEM1801);山西省自然科学基金(201901D111267);山西省领军人才项目(20190042)资助。 |
| |
| 摘 要： | 碳点(CDs)作为一种新型的零维碳基纳米材料,由于其优异的荧光性质、良好的生物兼容性、低细胞毒性以及丰富的表面官能团等性质,在荧光传感和生物医学领域具有巨大的应用潜力。特别是针对肿瘤弱酸性的微环境特点,设计pH响应型碳点来实现对肿瘤的特异性治疗将尤为重要。本文对近年来基于pH响应型碳点的研究工作进行了系统的调研,综述了pH响应型碳点的荧光机制及其在pH传感、生物成像及癌症治疗等生物医学领域的应用,并对pH响应型碳点目前面临的主要挑战以及未来发展的方向进行了展望。
|
| 关 键 词： | pH响应型碳点 荧光机制 pH传感 生物成像 癌症治疗 |
Fluorescence Mechanism and Biomedical Applications of pH-responsive Carbon Dots |
| |
| HE Song-jie,ZHANG Qing-mei,ZHANG Lu-peng,DU Xiu-juan,CHEN Feng-hua,LI Bing.Fluorescence Mechanism and Biomedical Applications of pH-responsive Carbon Dots[J].Chinese Journal of Luminescence,2022(1):137-151. |
| |
| Authors: | HE Song-jie ZHANG Qing-mei ZHANG Lu-peng DU Xiu-juan CHEN Feng-hua LI Bing |
| |
| Institution: | (School of Applied Science, Taiyuan University of Science and Technology, Taiyuan 030024, China;Fujian Provincial Key Laboratory of Quantum Manipulation and New Energy Materials, College of Physics and Energy, Fujian Normal University, Fuzhou 350117, China;School of Stomatology, Shanxi Medical University, Taiyuan 030051, China) |
| |
| Abstract: | As a new type of zero-dimensional carbon-based nanomaterials,carbon dots(CDs)have a great application potential in the fields of fluorescence sensing and biomedicine due to their excellent fluorescence properties,good biocompatibility,low cytotoxicity,and large surface functional groups.Especially given the weakly acidic microenvironment characteristics of tumors,it is crucial to design pH-responsive carbon dots to achieve specific treatment.This article has conducted a systematic investigation on the research work based on pH-responsive carbon dots in recent years and reviewed the fluorescence mechanism of pH-responsive carbon dots and their applications in biomedical fields such as pH sensing,bioimaging,and cancer treatment.Finally,the main challenges currently faced by pH-responsive carbon dots and the future development direction have been prospected. |
| |
| Keywords: | pH-responsive carbon dots fluorescence mechanism pH sensing bioimaging cancer treatment |
| 本文献已被 维普 等数据库收录！ |
|
