An approach to biologically important S‐heterocycles,dithiocarbamyls, and their relevant phosphono derivatives

The feasibility of insertions of carbanions between two sulfur atoms has been reported when 5‐(4‐chlorophenyl)‐4‐cyano‐1,2‐dithiol‐3‐thione ( 1 ) and tetramethylthiuram disulfide ( 17 ) were allowed to react with unsaturated 2a,b and active phosphonium salts 11a,b . The reactions afforded, mainly, 1,3‐dithiols 4a,b and 14a,b together with substituted thiophenes 10a,b and 16a,b . Reactions of 1 and 17 with α‐alkylthiomethyl phosphonates 24a,b afforded the phosphonates 25a,b and 26a,b , respectively.