Synthesis of 1‐(3,4‐dimethoxyphenylmethyl)‐3‐phenyl‐6,7,8‐trimethoxy‐3,4‐dihydroisoquinoline

In an attempt to ascertain the scope of using ethyl polyphosphate in the Bischler‐Napieralsky annelation reaction, a title compound was synthesized and reduced to the respective 1‐(3,4‐dimethoxyphenylmethyl)‐3‐phenyl‐6,7,8‐trimethoxy‐1,2,3,4‐tetrahydroisoquinoline.