Synthesis of 1H-pyrazolo[3,4-c]isoquinolin-1-ones by the condensation of cyclohexanone derivatives with 3-amino-1-phenyl-1H-pyrazol-5(4H)-one |
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Authors: | Dyachenko V D Sukach S M |
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Institution: | 1.Taras Shevchenko Lugansk National University, Oboronnaya ul. 2, Lugansk, 91011, Ukraine ; |
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Abstract: | The synthesis of 1H-pyrazolo3,4-c]isoquinolin-1-ones was carried out by reacting 3-aryl(heteryl)-2,4-diacetyl-5-hydroxy-5-methylcyclohexanones with 3-amino-1-phenyl-1H-pyrazol-5(4H)-one. The structure of the 7-acetyl-2,4,6,7,8,9-hexahydro-8-hydroxy-5,8-dimethyl-2-phenyl-6-(fur-2-yl)-1H-pyrazolo3,4-c]isoquinolin-1-one obtained was proved by X-ray diffraction analysis. |
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