Synthesis and complete assignment of NMR data of 20 chalcones |
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| Authors: | Hwang Doseok Hyun Jiye Jo Geunhyeong Koh Dongsoo Lim Yoongho |
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| Affiliation: | 1. Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Seoul 143‐701, Korea;2. Department of Applied Chemistry, Dongduk Women's University, Seoul 136‐714, Korea |
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| Abstract: | Chalcones, intermediates in flavonoid biosynthesis, can exhibit antibacterial, antiproliferative, and anti-inflammatory properties. Chalcones contain two benzene rings and both hydroxylated and methoxylated analogs are frequently produced by hydroxylases and O-methyltransferases in plant biosynthetic pathways. Assignments of NMR peaks in the spectra of hydroxylated and/or methoxylated chalcones can help in identifying novel chalcone derivatives isolated from natural sources by referencing these data against NMR spectra obtained from known chalcones. We report here the syntheses of 20 chalcones and complete assignments of (1)H and (13)C NMR spectra. |
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| Keywords: | NMR 1H NMR 13C NMR 2D NMR flavonoid chalcone |
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