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Determination of Hepatotoxic Pyrrolizidine Alkaloids in Gynura segetum by MEKC
Authors:Xueyong Qi  Shufang Wang  Bin Wu  Haibin Qu
Institution:1. Pharmaceutical Informatics Institute, Zhejiang University (Zijingang Campus), 310058, Hangzhou, People’s Republic of China
2. School of Pharmacy, Jiangsu University, 212013, Zhenjiang, People’s Republic of China
Abstract:A novel, rapid and sensitive micellar electrokinetic capillary chromatography method was developed for the separation and determination of two hepatotoxic pyrrolizidine alkaloids in Gynura segetum (Lour.) Merr. (Jusanqi) within 8 min. The method was successfully applied to the simultaneous determination of seneciphylline and senecionine in a Jusanqi sample.
Keywords:
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