Determination of Hepatotoxic Pyrrolizidine Alkaloids in Gynura segetum by MEKC |
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Authors: | Xueyong Qi Shufang Wang Bin Wu Haibin Qu |
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Institution: | 1. Pharmaceutical Informatics Institute, Zhejiang University (Zijingang Campus), 310058, Hangzhou, People’s Republic of China 2. School of Pharmacy, Jiangsu University, 212013, Zhenjiang, People’s Republic of China
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Abstract: | A novel, rapid and sensitive micellar electrokinetic capillary chromatography method was developed for the separation and determination of two hepatotoxic pyrrolizidine alkaloids in Gynura segetum (Lour.) Merr. (Jusanqi) within 8 min. The method was successfully applied to the simultaneous determination of seneciphylline and senecionine in a Jusanqi sample. |
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