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An electrochemical sensor based on octahedral composite modified glassy carbon electrode for voltammetric detection of cocaine
Authors:Elham Oveili  Shohreh Jahani  Omid Tayari  Abbas Jahanara  Zohreh Fazli  Zahra Aramesh-Boroujeni  Soroush Rashidi  Nadia Rezaei Zade Baravati  Mohammad Mehdi Foroughi
Affiliation:1. Department of Pharmaceutical Science, Islamic Azad University, Tehran, Iran;2. Noncommunicable Diseases Research Center, Bam University of Medical Sciences, Bam, Iran;3. Department of Civil Engineering, Central Tehran Branch, Islamic Azad University, Tehran, Iran;4. Department of Pediatrics, School of Medicine, Bam University of Medical Sciences, Bam, Iran;5. Department of Occupational Health and Safety, Bam University of Medical Sciences, Bam, Iran;6. Isfahan University of Medical Sciences, Isfahan, Iran;7. Department of Civil Engineering, Islamic Azad University, Kerman, Iran;8. Department of Nursing, School of Nursing and Midwifery, Bam University of Medical Sciences, Bam, Iran;9. Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran
Abstract:The current work aimed to fabricate a new cocaine sensor of octahedral palladium-doped cobaltite composite (Oh-Pd2+ : Co3O4-C) using a simple hydrothermal protocol. As-fabricated cocaine sensing approach was validated by various methods. Energy dispersive X-ray analysis, X-ray diffraction and scanning electron microscopy were recruited to characterize our charged modified composite. The electrode could sensitively detect cocaine, with a lengthy linear range (0.01 μM–900.0 μM) and a limit of detection (1.3 nM). The quantitative cocaine determination was achieved in the biological specimens using our modified electrode, the results of which displayed admirable outcomes.
Keywords:cocaine  composite  modified electrode  octahedral  voltammetry
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