|
|||||
|
|
Asymmetric intermolecular cyclopropanation of alkenes by diazoketones catalyzed by Halterman iron porphyrins |
|
| Authors: | Irène Nicolas Paul Le Maux |
| Institution: | a Ingénierie Chimique et Molécules pour le Vivant, Université de Rennes 1, Campus de Beaulieu, 35042 Rennes Cedex, France b Centre de Diffractométrie X, UMR 6226, Université de Rennes 1, Campus de Beaulieu, 35042 Rennes Cedex, France |
| Abstract: | The asymmetric addition of diazoacetophenone to styrene derivatives to give optically active cyclopropyl ketones (ee up to 80%) was carried out using chiral iron porphyrins as homogeneous catalysts. Intermolecular N-H functionalization of anilines by means of carbenoid-induced N-H insertion was also possible but without enantioselectivity. |
| Keywords: | Iron Diazoketone Halterman porphyrin Asymmetric cyclopropanation Cyclopropyl ketones |
| 本文献已被 ScienceDirect 等数据库收录！ | |