Synthesis of 3-aryl-4-chalcogen-2H-benzopyrans from 3-iodo-4-chalcogen-2H-benzopyrans using a Suzuki cross-coupling |
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Authors: | Benhur Godoi |
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Institution: | Laboratório de Síntese, Reatividade, Avaliação Farmacológica e Toxicidade de Organocalcogênios, CCNE, UFSM, Santa Maria, Rio Grande do Sul CEP 97105-900, Brazil |
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Abstract: | The Suzuki cross-coupling reaction of 3-iodo-4-chalcogen-2H-benzopyran derivatives with a variety of organoboron compounds in the presence of catalytic amount of palladium salt is described. This cross-coupling reaction proceeded cleanly and was performed with aryl boronic acids bearing electron-withdrawing, electron-donating, and neutral substituents, furnishing the corresponding products in moderate to good yields. |
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